Ann Kirschner began her career as a lecturer in Victorian literature at Princeton University, where she earned a Ph.D. in English. Her career as an entrepreneur in media and technology included the creation of satellite and internet businesses for the National Football League and Columbia University's online education company, Fathom. A frequent contributor to conferences and publications, Ann Kirschner was named one of New York Magazine's "Millennium New Yorkers" and honored as a distinguished graduate of Princeton University and University of Buffalo. She serves on the Board of Directors of Apollo, BPP, Public Agenda, the American Friends of Open University of Israel, and the Princeton University English Department Advisory Council.

Ann Kirschner is the author of Sala's Gift (Simon and Schuster/Free Press, 2006), the story of her mother's wartime rescue of letters from Nazi labor camps, published also in German, Polish, Italian, French, and Chinese editions. The original letters are in the permanent collection of the New York Public Library, and are the subject of a traveling exhibit in the United States and Europe, a theatrical play by Arlene Hutton, and a documentary film by Murray Nossel. Her next book Tombstone to Hollywood: The Adventures of Mrs. Wyatt Earp, will be published by Harper Collins.

She lives in New York City with her husband, Dr. Harold Weinberg, and is the mother of Elisabeth, Caroline, and Peter.