Chancellor Matthew Goldstein launched CUNY Honors College in 2001 to provide a globally competitive honors program for the most talented and academically gifted of New York's students.

The Honors College was designed in collaboration with CUNY senior colleges and programs. From the start, CUNY Honors was recognized for exceptional advising, hands-on internships and research opportunities, substantial community service and global learning opportunities, and a commitment to provide the skills and experiences for each student to excel in college and beyond.

The program includes a number of innovative programs: the four core seminars linking students with the history, arts, and resources of New York City; community service and service learning around the globe; internships that give students real work experience while in college; the Cultural Passport which gives students access to arts and culture in New York; and the Opportunities Fund, which allows each student to shape their own unique learning program.

The Honors College has grown from an inaugural class of 189 to a current student body of over 1200 students.

In October 2006, a generous gift from Linda and William Macaulay, a 1966 Honors graduate of City College, enabled the Honors College to purchase and extensively renovate a landmark building on 67th street, to serve as the home of the honors college. In honor of Mr. Macaulay's gift, the college was renamed William E. Macaulay Honors College at the City University of New York.

The new building was officially opened on April 17, 2008, with a dedication attended by nearly 200 friends of Macaulay, including Senator Charles Schumer, Chancellor Goldstein, and New York City Councilmember Gale Brewer.